Ikimenyetso Cyubuzima Cyiza Kumenyekanisha items Ibintu 5-6）

Intego yo kugerageza】
Fase pancreatic lipase (fPL): pancreas ni glande ya kabiri nini igogora mu mubiri winyamanswa (iyambere ni umwijima), iherereye munda yimbere yumubiri, igabanijwemo ibumoso n iburyo.Igikorwa cyacyo nyamukuru ni ugusohora imisemburo ikenewe kumubiri.Pancreatitis igabanyijemo pancreatite ikaze na pancreatite idakira.Ibyangiritse byatewe nabambere ahanini byigihe gito, mugihe ibyanyuma bisiga fibrosis ihoraho hamwe na atrophy mugihe cyo gutwikwa kenshi.Muri byo, pancreatite idakira ihwanye na 2/3 bya pancreatite y'injangwe.
Cholyglycine (CG) ni imwe muri acide ya cholike ya conjugate ikorwa no guhuza aside ya cholike na glycine.Acide Glycocholic nikintu cyingenzi cya aside aside muri serumu mugihe cyo gutwita.Iyo selile yumwijima yangiritse, gufata CG ningirangingo zumwijima byagabanutse, bituma kwiyongera kwa CG mumaraso.Muri cholestasis, gusohora aside aside ya cholike n'umwijima birabangamiwe, kandi ibikubiye muri CG byagarutse mu maraso byiyongera, ari na byo byongera ibikubiye muri CG mu maraso. Acide ya bile ibikwa mu mitsi, ishobora kuvaho. unyuze mu muyoboro wa hepatike nyuma yo kurya.Mu buryo nk'ubwo, indwara z'umwijima no guhagarika imiyoboro y'amaraso bishobora gutera indangagaciro idasanzwe.
Cystatin C ni imwe muri poroteyine za cystatine.Igikorwa cyingenzi cya physiologique ni uguhuza ibikorwa bya protease ya sisitemu, ifite ingaruka zikomeye zo kubuza cathepsin B, papain, protease protease, na cathepsin H na I narekuwe na lysosomes.Ifite uruhare runini muri metabolism ya peptide na proteine ​​zo mu nda, cyane cyane muri metabolisme ya kolagen, ishobora hydrolyze zimwe na zimwe za prehormone ikayirekura mu ngingo zigamije kugira uruhare mu binyabuzima.Amaraso yubwonko bwamaraso hamwe na amyloidose nindwara ifitanye isano itaziguye na mutation ya gene ya cystatine C, ishobora gutera ubwonko bwubwonko bwangirika, kuva ubwonko bwubwonko nizindi ngaruka zikomeye.Impyiko niho hantu honyine hashobora gukwirakwizwa cystatine C, kandi umusaruro wa cystatine C uhoraho.Urwego rwa serumu cystatin C ahanini rushingiye kuri GFR, nikimenyetso cyiza cya endogenous cyerekana impinduka za GFR.Imihindagurikire yibindi bintu byamazi yumubiri nabyo bifitanye isano nindwara zitandukanye.
NT-proBNP (N-terminal pro-brain natriuretic peptide), izwi kandi ku izina rya B yo mu bwoko bwa diuretic peptide, ni imisemburo ya poroteyine isohorwa na cardiomyocytes mu mitsi y'umutima.Iyo umuvuduko wamaraso wiyongereye, kwaguka kwamashanyarazi, hypertrophy myocardial, cyangwa umuvuduko wa myocardium wiyongera, prursor ya NT-proBNP, proBNP (igizwe na acide 108 amine), isohoka mumaraso na cardiomyocytes.
Injangwe ya allergen IgE yose (fTIgE): IgE ni ubwoko bwa immunoglobuline (Ig) ifite uburemere bwa molekile ya 188kD nibirimo bike cyane muri serumu.Ubusanzwe ikoreshwa mugupima indwara ya allergique.Byongeye kandi, irashobora kandi gufasha mugupima indwara zanduye parasitike na myeloma nyinshi.1. Imyitwarire ya allergique: iyo reaction ya allergique ibaye, biganisha ku kwiyongera kwa allerge lgE.Iyo hejuru ya allergen lgE, niko reaction ya allergique ikomeye.2. Indwara ya parasite: nyuma yuko itungo ryanduye parasite, allergene lgE nayo irashobora kwiyongera, muri rusange ikaba ifitanye isano na allergie yoroheje iterwa na poroteyine za parasite.Byongeye kandi, amakuru avuga ko kanseri ishobora no kugira uruhare mu kuzamuka kwa IgE yose.
Principle Ihame ryo gutahura】
Iki gicuruzwa gikoresha fluorescence immunochromatography kugirango umenye umubare wibiri muri fPL / CG / fCysC / fNT-proBNP / fTIgE mumaraso yinjangwe.Ihame shingiro ni uko nitrocellulose membrane irangwa nimirongo ya T na C, naho umurongo wa T ugashyirwa hamwe na antibody a imenya antigen.Igikoresho cyo guhambira cyatewe nindi fluorescent nanomaterial yanditseho antibody b ishobora kumenya antigen.Antibody iri murugero ihuza na nanomaterial yanditseho antibody b kugirango ikore urwego, hanyuma ihuza T-umurongo wa antibody A kugirango ikore sandwich.Iyo urumuri rwo kwishima rurabagirana, nanomaterial isohora ibimenyetso bya fluorescent.Ubwinshi bwikimenyetso bwari bufitanye isano neza na antigen yibanze muri sample.